Pharmaceutical Effluent Testing
This is a general purpose method for the identification and simultaneous measurement of purgeable volatile organic compounds in surface water, ground water, and drinking water in any stage of treatment.
The method is applicable to a wide range of organic compounds, including the four trihalomethane disinfection by-products, that have sufficiently high volatility and low water solubility to be removed from water samples with purge and trap procedures.
A critical regulatory requirement for industries involved in the discharge of wastewater containing pharmaceutical contaminants.
According to 40 CFR Part 439, facilities engaged in pharmaceutical manufacturing must comply with stringent guidelines to ensure that their wastewater is treated and tested appropriately to prevent environmental contamination.
The EPA has described the measurement of purgeable organic compounds in water by capillary column gas chromatography mass spectrometry, in their whitepaper on the scope and application of testing using EPA Method 542.2.
Excerpt from EPA 542.2: Summary of Method
“Volatile organic compounds and surrogates with low water solubility are extracted (purged) from the sample matrix by bubbling an inert gas through the aqueous sample. Purged sample components are trapped in a tube containing suitable sorbent materials. When purging is complete, the sorbent tube is heated and backflushed with helium to desorb the trapped sample components into a capillary gas chromatography (GC) column interfaced to a mass spectrometer (MS). The column is temperature programmed to facilitate the separation of the method analytes which are then detected with the MS. Compounds eluting from the GC column are identified by comparing their measured mass spectra and retention times to reference spectra and retention times in a data base. Reference spectra and retention times for analytes are obtained by the measurement of calibration standards under the same conditions used for samples.”
Teklab is proud to offer comprehensive testing services to meet these needs for your regulatory compliance. We have stringent protocols that both streamline our analytical process and enhance our customer experience.
This is through our 42 plus years of dedicated service in the environmental testing industry, which has enabled our tenured lab personnel and operations management to develop our internal standard operating procedure that is built to optimize the existing industry recognized ISO-based TNI standards for environmental laboratories.
As a NELAP accredited environmental testing laboratory, Teklab specializes in the advanced analysis required for wastewater effluent and groundwater monitoring in the Pharmaceutical Manufacturing Industry (PMI).
Our team utilizes state-of-the-art technology and adheres to rigorous quality control standards to provide precise, reliable data that ensures compliance with federal regulations, safeguarding both public health and the environment.
The industry-leading team at Teklab utilizes our specialized SOP that serves as a guide for our chemists and analysts, this eliminates many issues and streamlines our sample processing time to below average compared other labs turn-around-time.
→ The table below list many analytes commonly tested for at Teklab using EPA method 524.2 PMI.
Our volatile organics department routinely performs specialty analysis like EPA 524.2 PMI for other environmental testing labs. Teklab also analyses PMI compounds by Methods EPA 1666 and EPA1671.
If you have any questions regarding our PMI environmental testing services, please use the Contact Us page to send us a request or to receive a risk-free quotation.